Wellbutrin (Bupropion) is a drug that is used for the treatment of depression as well as to help people quit smoking. It has become a very popular medication to treat depression because it is considered to have a minimal side effect profile compared to many other drugs. I've quit an anti-depressant cold turkey and was just fine. I'd try it for a few days, and if you experience any symptoms, slowly start taking them again before weaning off. I quit Wellbutrin cold turkey and I am now treating my anxiety with meditation therapy (breathing) and yoga. I experience much more relief than was possible with Wellbutrin. Now I can't say that my experience is mirroring yours (but it is possible). egibs, I'm with Pledge's advice. I, too, tried to get off Lexapro, it's a rough cold turkey. Taper off is less uncomfortable. Go back on at a lower dose if you have any and cut down slowly, your body will tell you the pace for you. mbid; Do not stop Wellbutrin cold turkey. You need to be brought off of that medication gradually. Your heart could start racing, you could have a seizure. When I lost my job, and my insurance, I had to quit cold turkey, because I couldn’t afford them. I had 2 episodes, a month apart, of being totally delusional, and hallucinating, audio and visual! Both times it lasted for a whole week. My partner went out and bought them for me, about $250.00! Then I signed up with a People’s Plan for reduced prices. That’s the only way I stayed sane. Meilleure réponse: I quit Wellbutrin cold turkey, but I was also taking Zoloft at the time. I found the Zoloft to be much tougher to shake. My advice would be to make sure you let the doctor that prescribed the medication know of your intention. Another good idea is to make sure that someone close to you is aware. How to Stop Taking Wellbutrin. Wellbutrin, or bupropion, is classified as an antidepressant and is usually used to treat depression—though, the drug is also used as a smoking cessation aid under the name Zyban. Since Wellbutrin affects b.